L-Theanine vs Rhodiola

for stress

Stronger evidence: tie

Stronger effect: tie

Safety: Rhodiola has the more serious interaction profile (minor vs uncertain).

For stress, the two are evidence-matched; the difference is in effect and safety.

L-Theanine

grade C low certainty

small calming effect; often paired with caffeine to smooth its edge

100–200 mg

Rhodiola

grade C low certainty

preliminary stress/burnout benefit; low-quality evidence

sources: PMID:00000022 · PMID:00000032