Omega-3 vs Lion's Mane

for cognition

Stronger evidence: Lion's Mane

Stronger effect: unknown

Safety: Omega-3 carries a serious interaction; Lion's Mane has none recorded.

For cognition, Lion's Mane has the stronger evidence grade.

Omega-3

not well studied very-low certainty

not adequately studied for cognition in healthy adults

Lion's Mane

grade C low certainty

early, small studies suggest a modest cognitive effect

~1 g/day, adults
sources: PMID:00000010