Omega-3 vs Caffeine
for cognition
Stronger evidence: Caffeine
Stronger effect: unknown
Safety: Omega-3 has the more serious interaction profile (serious vs minor).
For cognition, Caffeine has the stronger evidence grade.
Caffeine
grade A high certainty
reliably improves alertness, reaction time, and vigilance
40–200 mg, adults
sources: PMID:00000020