Omega-3 vs Caffeine

for cognition

Stronger evidence: Caffeine

Stronger effect: unknown

Safety: Omega-3 has the more serious interaction profile (serious vs minor).

For cognition, Caffeine has the stronger evidence grade.

Omega-3

not well studied very-low certainty

not adequately studied for cognition in healthy adults

Caffeine

grade A high certainty

reliably improves alertness, reaction time, and vigilance

40–200 mg, adults
sources: PMID:00000020