Creatine vs Omega-3

for cognition

Stronger evidence: Creatine

Stronger effect: unknown

Safety: Omega-3 carries a serious interaction; Creatine has none recorded.

For cognition, Creatine has the stronger evidence grade.

Creatine

grade B moderate certainty

benefit to cognition, clearest under sleep deprivation or stress

5 g/day

Omega-3

not well studied very-low certainty

not adequately studied for cognition in healthy adults

sources: PMID:00000004